Description
Buy retatrutide — research-grade triple-agonist peptide targeting GLP-1, GIP, and glucagon receptors simultaneously. Available in 5mg, 10mg, 20mg, and 30mg vials with 99%+ purity verified by third-party HPLC and mass spectrometry. When you buy retatrutide from PSPeptides, every batch ships with a certificate of analysis from an independent US laboratory.
What Is Retatrutide (LY3437943)?
Retatrutide (development code LY3437943) is a 39-amino acid synthetic peptide developed by Eli Lilly as the first triple-receptor agonist targeting GLP-1R, GIPR, and GCGR in a single molecule. Researchers who buy retatrutide for laboratory studies use it to investigate metabolic pathways involving appetite regulation, energy expenditure, lipolysis, and hepatic fat metabolism. Learn more in our complete retatrutide research guide.
Key Research Applications
- Metabolic Research: Simultaneous activation of three receptors modulates energy balance through complementary mechanisms not achievable with single-agonist compounds.
- Obesity and Weight Studies: Published Phase 2 data (NEJM, 2023) showed up to 24.2% mean body weight reduction at 48 weeks.
- Type 2 Diabetes Models: Phase 3 TRANSCEND-T2D-1 data demonstrated HbA1c reductions of 1.7-2.0% and mean weight loss of 36.6 lbs over 40 weeks.
- Hepatic Fat and MASH Research: Glucagon receptor activation promotes lipolysis and fatty acid oxidation in the liver, reducing hepatic fat content.
Buy Retatrutide: Product Specifications
| Amount | 5mg | 10mg | 20mg | 30mg (lyophilized vials) |
| Purity | 99%+ (third-party HPLC and mass spectrometry) |
| Formula | C239H343N53O70 | MW: 5,414.9 Da | CAS: 2381089-83-2 |
| Form | Lyophilized powder |
| Storage | -20C or below (lyophilized); 2-8C after reconstitution (use within 28 days) |
| Testing | Batch-specific COA included with every order |
| Origin | US manufactured, third-party tested |


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