Description
buy TB-500 (Thymosin Beta-4 Fragment) — a synthetic research peptide analog of the naturally occurring thymosin beta-4 protein. Each vial contains lyophilized powder at ≥99% purity (HPLC and mass spectrometry verified), US manufactured, with a batch-specific Certificate of Analysis included.
What Is TB-500?
TB-500 is a 43-amino acid synthetic peptide corresponding to the active region of thymosin beta-4 (Tβ4), a protein found in virtually every human and animal cell. When researchers buy TB-500 for laboratory use, they gain access to one of the most studied tissue-repair signaling peptides in preclinical science. It promotes actin polymerization and cytoskeletal remodeling, two processes central to cell migration, differentiation, and regenerative cascades. Learn more in our complete TB-500 guide.
this peptide is frequently studied alongside BPC-157 in what the research community calls the “Wolverine Stack” — a dual-peptide protocol targeting both systemic and localized tissue repair mechanisms. For a direct comparison, see our BPC-157 vs this peptide comparison guide.
Key Research Applications
- Connective Tissue Regeneration: thymosin beta-4 promotes collagen remodeling and fibroblast migration, supporting wound-healing models in connective tissue research.
- Musculoskeletal Recovery: Preclinical studies examine the peptide’s role in skeletal muscle repair, tendon healing, and reducing fibrotic scar tissue formation.
- Anti-Inflammatory Signaling: Research demonstrates this fragment’s ability to downregulate pro-inflammatory cytokines and reduce localized inflammation in injury models.
- Cardiovascular Tissue Repair: Studies have investigated thymosin beta-4 in cardiac regeneration models, particularly cardiomyocyte migration and neovascularization.
- Hair Follicle Activation: Thymosin beta-4 has been shown to activate quiescent hair follicle stem cells, making it a subject of active hair biology research.
- Systemic Distribution Models: Unlike many locally acting peptides, this research peptide’s low molecular weight allows systemic distribution after administration, expanding its research utility.
Product Specifications
| Peptide | thymosin beta-4 fragment (Thymosin Beta-4 Fragment) |
| CAS Number | 77591-33-4 |
| Purity | ≥99% (third-party HPLC and mass spectrometry verified) |
| Form | Lyophilized powder |
| Storage | −20°C long-term; 4°C short-term (avoid repeated freeze-thaw cycles) |
| Testing | Batch-specific COA included |
| Origin | US manufactured |


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