Description
Buy Ipamorelin — a research-grade synthetic pentapeptide growth hormone secretagogue with exceptional receptor selectivity. Ipamorelin (CAS: 170851-70-4) activates GHS-R1a to trigger GH release from pituitary somatotrophs without elevating cortisol, prolactin, or aldosterone. Lyophilized, US-manufactured, and verified at ≥99% purity by HPLC and mass spectrometry, with a batch-specific COA included. Researchers looking to buy ipamorelin will find PSPeptides meets the highest standards for purity and reliability in 2026.
What Is Ipamorelin?
Ipamorelin is a selective pentapeptide growth hormone secretagogue (GHS) that mimics ghrelin’s action at the GHS-R1a receptor on pituitary somatotroph cells. Its pentapeptide structure — incorporating an Aib (alpha-aminoisobutyric acid) residue and a D-2-Nal modification — confer potent GHS-R1a binding with minimal off-target activity. This structural selectivity is why researchers who want to buy ipamorelin choose it over earlier-generation secretagogues such as GHRP-6 or GHRP-2. For a comprehensive background on ipamorelin’s pharmacology and research applications, see our CJC-1295 / Ipamorelin growth hormone guide.
Key Research Applications
- Selective GH secretion studies: Ipamorelin activates GHS-R1a without significant ACTH or cortisol elevation, making it the gold-standard tool for isolating GH secretagogue receptor pharmacology in clean experimental models.
- Synergistic GH axis research: Most who buy ipamorelin pair it with CJC-1295 No DAC (Mod GRF 1-29) to simultaneously activate complementary GHRH and ghrelin receptor pathways for amplified GH output.
- Bone metabolism and mineral density research: Preclinical models demonstrate that ipamorelin increases bone mineral content and bone formation markers, creating relevant research tools for osteoporosis and bone density studies.
- Body composition and lean mass studies: GH pulses driven by ipamorelin support lean mass and body composition research in rodent and in vitro settings, with applications for metabolic research models.
- Age-related GH decline models: Ipamorelin is used in aging-model research to investigate restored physiological GH pulsatility, helping researchers understand the mechanisms behind age-associated GH decline.
- GHS receptor pharmacology: Researchers buy ipamorelin as a reference compound in structure-activity relationship (SAR) studies investigating next-generation selective secretagogues and GHS-R1a biased agonism.
Product Specifications
| Peptide | Ipamorelin |
| CAS Number | 170851-70-4 |
| Amount | 5 mg per vial |
| Molecular Formula | C₃₈H₄₉N₉O₅ |
| Molecular Weight | 711.85 g/mol |
| Purity | ≥99% (third-party HPLC and mass spectrometry) |
| Form | Lyophilized (freeze-dried) powder |
| Storage | Lyophilized: −20°C. Reconstituted: 2–8°C, use within 4 weeks. |
| Testing | Batch-specific COA included |
| Origin | US manufactured |
| Intended Use | Laboratory and research use only. Not for human consumption. |
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